Cretinism

__Cretinism__ NM and PS Cretinism is the insufficient thyroid production which results in physical stunting and mental retardation. It is donated as an autosomal recessive trait. Cretinism is located on the x chromosome. Congenital hypothyroidism, or the deficiency of thyroid hormones, can be endemic, genetic, or sporadic. Cretin is a term that is used to describe someone who is affected by this disease. In the 19th and 20th century, the term was used for medical purposes, but recently it has been used as derogatory term for a person who shows stupid behavior.

 **Symptoms:** ** Causes and Risk Factors **   After a medical examination, blood tests will be taken. A low T4 and a high TSH means that the child has cretinism. Early Newborn screening can be used to diagnosis the disease. ** Prognosis ** Early diagnosis will result in a good outcome for the infant, in both growth and mental ability. Without treatment, there is little hope for a normal mental state. Without thyroid hormones, the child will most likely grow up with a mental disability.  If cretinism is caught early on, it can be easily reversed. Infants treated within the first two months of life with usually develop normally. Replacement therapy is a standard procedure. The most common treatment is a thyroid hormone supplementation. These hormones can be extracted from animals or can be synthetic hormones.  **<span style="COLOR: rgb(236,95,203)"> Statistics ** <span style="COLOR: rgb(236,95,203)"> <span style="COLOR: rgb(236,95,203)">Endemic cretinism is very common in areas of southern Europe around the Alps. Women over 50 and men over 60 may be at risk for thyroid problems. Cretinism occurs at a rate of 1 out of every 6,000 births <span style="COLOR: rgb(236,95,203)">. http://www.thyroidmanager.org/Chapter20/figures20/figure5.jpg
 * <span style="COLOR: rgb(235,111,111)">constant drooling
 * <span style="COLOR: rgb(235,111,111)">a swayback
 * <span style="COLOR: rgb(235,111,111)">a potbelly
 * <span style="COLOR: rgb(235,111,111)">adult stature without treatment is about 1 to 1.6 meters
 * <span style="COLOR: rgb(235,111,111)">poorly formed teeth
 * <span style="COLOR: rgb(235,111,111)">swelling around the eyes
 * <span style="COLOR: rgb(235,111,111)">dry skin
 * <span style="COLOR: rgb(235,111,111)">low energy
 * <span style="COLOR: rgb(235,111,111)">memory lapses
 * <span style="COLOR: rgb(235,111,111)">thick protruding tongue
 * <span style="COLOR: rgb(235,111,111)">choking episodes
 * <span style="COLOR: rgb(235,111,111)">constipation
 * <span style="COLOR: rgb(235,111,111)">prolonged jaundice
 * <span style="COLOR: rgb(242,99,206)">thyroid gland dysfunction
 * <span style="COLOR: rgb(242,99,206)">family history of thyroid problems
 * <span style="COLOR: rgb(242,99,206)">high cholesterol
 * <span style="COLOR: rgb(242,99,206)">men over 60 and women over 60 are at higher risk
 * Diagnosis**
 * Treatment**
 * <span style="COLOR: rgb(216,65,236)">This Picture shows one normal person and three people with Myxedematous endemic cretinism from the Democratic Republic of Congo. The three in the bottom of the picture have severe hypothyroidism with dwarfism, retarded sexual development, puffy features, dry skin and hair and severe mental retardation. **

http://library.thinkquest.org/19347/media/Goitre.jpg <span style="COLOR: rgb(233,22,22)"><span style="COLOR: rgb(236,14,14)">**This woman above is suffering from simple goitre, or** **an enlarged<span style="COLOR: rgb(3,2,2)"> <span style="COLOR: rgb(240,25,25)">thyroid gland. **

http://www.e-radiography.net/radpath/c/cretinism1.jpeg
 * <span style="COLOR: rgb(61,244,42)">A protruding tongue is a symptom of cretinism. **

<span style="COLOR: rgb(176,165,7)"> <span style="COLOR: rgb(214,132,5)">**<span style="COLOR: rgb(193,163,11)"> Interesting info **

<span style="COLOR: rgb(201,178,8)">__**Iodine Deficiency Video in Indonesia-**__ **Cretinism  <  ** http://www.youtube.com/watch?v=NV4X5cXaf7Y

In this video, the people of the town aren't getting any iodine in there food so cretinism is becoming a problem.

"Cretinism" __Wikapedia Foundation"__ 31 March 2008. http://en.wikipedia.org/wiki/Cretinism.
 * __Biography__**

"Cretinism-congenital hypothyroidism" __E-radiology.__ 4 April 2008. http://www.e-radiography.net/radpath/c/cretinism.htm#TOP.

"Cretinism" __Health Scout.__ 2001-2008. The Health Central Network, 4 April 2008. http://www.healthscout.com/ency/68/34/main.html#DiagnosisofHypothyroidism.

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__Comments__

A note from your teacher...you may want to check for spelling and grammar errors. Also, don't forget other interesting info and more info on how it may be inherited. Be sure to check the rubric to see if you have accomplished maximum points.

Your page is very colorful and very interesting, we learned a lot about this disease. And the pictures help a lot, too. ~Cri-du-Chat (RS and UP)

We enjoy your colors and pictures/images. They are rad. Also, we learned a lot about this rare disease. It's interesting... Love, HK & JM

Yo what up my my peeps. Your page is sick-nasty off the chain fo' real. I totally diggin the color and the sweet pics. You deserve a 100% fo' sho'. Peace G's. PR & EN

Your page is very informative. Nice job on the page! The pictures are very intresting. CL & JH

Moment of Zen